1. Brener MI, Lurz P, Hausleiter J, Rodés-Cabau J, Fam N, Kodali SK, et al. Right ventricularpulmonary arterial coupling and afterload reserve in patients undergoing transcatheter tricuspid valve repair. J Am Coll Cardiol 2022;79:448–461. https://doi.org/10.1016/j. jacc. 2021.11.031. Right ventricular-Pulmonary arterial coupling is a powerful, independent predictor of allcause mortality in patients with tricuspid regurgitation undergoing transcatheter tricuspid valve repair. These data suggest that the TAPSE/Pulmonary artery systolic pressure ratio can inform patient selection and prognostication following transcatheter tricuspid valve repair.

2. Cahill TJ, Pibarot P, Yu X, Babaliaros V, Blanke P, Clavel MA, et al. Impact of right ventriclepulmonary artery coupling on clinical outcomes in the PARTNER 3 trial. JACC Cardiovasc Interv 2022;15:1823–1833. https://doi.org/10.1016/j. jcin.2022.07.005. In patients with symptomatic severe aortic stenosis at low surgical risk undergoing trans-catheter aortic valve replacement or surgical aortic valve replacement, baseline right ventricle – Pulmonary artery uncoupling defined by TAPSE/Pulmonary artery systoli pressure ≤0.55 mm Hg-was associated with adverse clinical outcomes at 2 years, including all-cause mortality, cardiovascular mortality, and rehospitalization.