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Haemodynamic impact of MitraClip in patients with functional mitral regurgitation and pulmonary hypertension.

Dottor Mandurino Mirizzi, qual è il take home message del vostro lavoro?
La selezione dei pazienti per la riparazione transcatetere valvolare mitralica con MitraClip rappresenta ancora oggi una sfida. In particolare, per i pazienti affetti da insufficienza mitralica funzionale (FMR) severa l’intervento di MitraClip si è rivelato essere una valida opzione solo in casi selezionati.

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Outcomes After Transcatheter Aortic Valve Replacement in Bicuspid Versus Tricuspid Anatomy. A Systematic Review and Meta-Analysis.

Objectives: The aim of this study was to compare the feasibility, safety, and clinical outcomes of transcatheter aortic valve replacement (TAVR) in bicuspid aortic valve (BAV) versus tricuspid aortic valve (TAV) stenosis.
Background: At present, limited observational data exist supporting TAVR in the context of bicuspid anatomy.
Methods: Primary endpoints were 1-year survival and device success. Secondary endpoints included moderate to severe paravalvular leak (PVL) and a composite endpoint of periprocedural complications; incidence rates of individual procedural endpoints were also explored individually.

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Short dual antiplatelet therapy followed by P2Y12 inhibitor monotherapy vs. prolonged dual antiplatelet therapy after percutaneous coronary intervention with second-generation drug-eluting stents: a systematic review and meta-analysis of randomized clinical trials.

Abstract Aims: After percutaneous coronary intervention (PCI) with second-generation drug-eluting stent (DES), whether short dual antiplatelet therapy (DAPT) followed by single antiplatelet therapy (SAPT) with

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